The inside rear view mirror may become discolored or difficult to see clearly from. A revised mirror is available to correct this concern.Google+
Car Problem Reports
Lexus GS350 The Inside Rear View Mirror May Become Discolored
Lexus GS350 Problem
Average Mileage: 72,714 mi (38,000 mi - 103,000 mi)
Visitor, 2007 Lexus GS350, 38,000 mi
the rear view mirror looks like its all scratched up from the inside out getting hard to use
Visitor, 2007 Lexus GS350, 80,000 mi
2007 Lexus GS350 interior rear view mirror looks scratched (the mirror coating inside the housing)
Rear view mirror has dark spots.
Visitor, 2007 Lexus GS350, 103,000 mi
Darkened spots on rear view mirror.
Getting it replaced
I have the same issue and my GS350 is a 2006
The reflective coating is wearing off.
Visitor, 2007 Lexus GS350, 83,000 mi
mirror developing "scratches"
The rear view mirror got smoggy and difficult to see in certain condition.
I think this is a poor quality dfective mirror.