I have error codes on a es300 of PO300,PO301,PO303,PO305 and P1135

Upstream between the engine and firewall. P0300 - P0305 = misfires on cylinders 1, 3, & 5. Along with replacing the O2 sensors, you might clean or replace the Variable Valve Timing oil control valve filters.

Replace both unless you had one changed recently, they function as a unit. Clear codes after installation one fault code will set other codes when it becomes a fuel and air issue. (which it does.) If you don't have a scan tool, stop by any Auto Zone, Advance Auto Parts etc. and they should do it free of charge. Good Luck, Kool Tool. Downstream is the lower one.