2014 Acura TL v6 drove with no engine air filter for 2100miles

that don't sound to good. did someone steal your air filter or what?

Not good for the MAF sensor , but seriously , unless your engine was driven in sand for a while ,I wouldn't worry about any other damage. I know it's a whole nother breed , but I drove my '94 Dodge Intrepid (3.3L pushrod engine!) for almost 200K without a filter , and it NEVER showed any signs of damage/wear. Maintained consistent 25mpg up until 296,000 , when the trans gave out after putting ADVANCE Auto parts ATF+4 trans fluid in it instead of ChyslerATF.