2003 Alero V6 3.4L question.. What in the world is wrong with my car??

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My car started idling rough at first then couple of days went by and i noticed it started hesitating when accelerating past 45. Then a day later it did it again only this time the service engine soon light started blinking while accelerating past 60-70mph. I immediately replaced spark plugs n wires. same thing. i replaced ignition coils with MSD coils set of 3. still same thing. i had also replaced MAF sensor and TPS sensor but problem still persists. Took it to autozone to get it scanned and they said i had multiple misfires. A misfire on cylinder 2 and random. I thought the new ignition coils and spark plugs n wires would do it but obviously did not. Help please im in the dark.n Is my engine gone to crap?