I hit a bump in a driveway and now the car runs real ruff and the transmission

It is unlikely the two things are related.

That must have been some bump! .. How much damage was done to the undercarriage? .. Engine oil or transmission fluid leaking out?? .. Oil pan bent up into the crankshaft making strange noise?? .. Broken exhaust line components?? .. We could better answer your question if we had more details.