I have a misfire on 5&6 in my 03 Durango. i have replace everything

Yes I have done a compression test. Good on all cylinders.

Possibilities > #6 - #5 plug wires crossed ......... No injector *pulse* ......... Vacuum leak **Hands-on** help from qualified personnel is likely required. Good luck!

Check for vacuum leak, nothing found. Wires are not crossed and replaced and tested all injectors

Ok - Do ALL injectors have a *pulse signal* from the injector driver module ??? Test with noid light. **Between the TWO posted answers you received here - the problem has ‘got’ to be found!!** Good luck with it!

I don’t have a noid light. I will see what I can do. I really don’t want to bring at to mechanic, I don’t have that kind of money. Do you know if I can rent a noid light? Thanks once again

Yes - parts store should have a noid light kit - pick the one that matches the wire connector .. While engine is cranking / running - noid light should flash steadily. An alternative is to take a VERY LONG screwdriver and use it as a stethoscope - put tip on injector - put ear on handle - should hear injector clicking while engine is running - listen to a couple that’s know to be ok so you’ll know exactly what to listen for .. IF injector is clicking - should be spraying fuel into cylinder. Noid light is just a lot easier. Be careful working around *rotating* engine / accessories!

Ok I will try that. But if there is no constant click what needs to be done?

Then it is no longer a diy repair! Seek out professional *hands-on* help.. This will take an experienced technician to determine the exact failure - there is no way to guide you through the troubleshooting flow chart here online.