2.3 4cyl intermittent misfire cyls 1&2 rough idle stumbles high gear 2ooo rpm

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check emgine light on codes imtermittent misfire cyls 1&2 plugs/wires/iac mod/pcv/tps replaced,also checked for vacuum leaks cleaned map sensor and intake manifold/trottle body. Vacuum check 18 to 20 lbs unsteady runs rough idle to 2000 rpm stumble in high gears under load runs fine at higher rpms poor gas milege Please help put this problem to rest.210,000 miles