none of my doors on my Sienna will lock. Fuse was fine.

Hello, Not to discourage you, but the door lock system on this vehicle is robust. The point of failure could be in a number of positions. from the instrument cluster, the fuse box, one of a few connectors and grounds. The solution may be simple, but finding it may not be. I recommend replacing the fuse and looking for signs of corrosion, checking the gauge fuse as well, and checking the dome fuse under the hood. If those are all fine, and no signs of damage or corrosion, seek professional assistance. If you are having issues with the instrument cluster, it is likely causing the issues with the doors.