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Hi, this is Bo, an auto expert on RepairPal's Car Genius team! A cylinder 1 misfire in your 2008 Mercedes-Benz C300 is like your engine sneezing, and it could be as simple as a worn-out spark plug or coil pack. These parts tend to age like milk, not wine, so checking those first is a good idea. If they’re fine, it could be a clogged fuel injector not feeding cylinder 1 the juice it needs. Given it just happened, you might get lucky with a quick swap of the plug or coil, and you’ll be back on the road without that pesky check engine light staring at you! If you need any further advice or want help finding a trusted RepairPal shop in your area, please feel free to call us at 877-913-1554!