My 02 lexus gs 300 alarm won't wk @ times w/any of the buttons..not evn trunk or

did u try to replace the locks? If you are in Baltimore maryland,bring the car by the shop and we can take a look at it for you we are at 600W.PATAPSCO AVE. BALTIMORE,MD 21225 443)467-6662

May be a failed/failing door lock solenoid, make sure the transponder battery is good if it just won't work of the transponder. Again if replacing battery in transponder take the opportunity to clean the guts of transponder with a circuit board cleaner.