Why does the radio show no audio and no power

Hi, my name is Devin. I am an auto repair expert with the Car Genius team here at RepairPal. I'm sorry to hear you're having trouble with your ES350. When the radio has no power and no sound output, it could be caused by a blown fuse, a faulty amplifier, or an internal issue with the head unit itself. Start by checking the fuse box for a blown fuse related to the radio or amplifier. Sometimes, these fuses are located under the dash or in a separate box near the engine compartment. If the fuses are intact, the amplifier (if equipped) might not be powering up, which can also result in no audio. The radio head unit might have failed or lost its connection if these components seem fine. A quick check with a multimeter or a professional diagnostic tool can help narrow it down. If you need more advice, have any other questions about your vehicle, or would like to get connected to a RepairPal Certified shop near you, we have you covered. Give us a call at 877-913-1554, and we will happily help you out!