All doors locked-Door panel's power locks, fob & key dont work

Hi, Thanks so, so much for your response. I will try to replace the fob battery. I will also see if there is a way to gain access the vehicle's hood in order to try to disconnect the anti-theft system to see if that may work. The fob light blinks only when the panic button was pressed, but nothing occurred at all when the other buttons were pressed. The car battery is fairly new & the connections were checked when this problem occurred. Would you happen to have any other suggestions that I could also try? And I was wondering, could the actuators be a possible issue? Thanks again!

Yes, the actuators could be the problem, but all at the same time isn't likely at all. Disconnecting the anti-theft system would require software modification, and if the anti-theft system can't talk to the ECM and BCM, it will not allow the vehicle to function. If only one button makes the light come on the key fob, I wonder if it has somehow been liquid damaged.

It's crazy because I used the car that day, (this happened Thursday) I was out and about, in & out the car, and everything was great. No tell tale signs at all. It wasn't until I parked it in my driveway at the end of my day, that this was a problem, and I couldn't unlock the doors by the power lock on the door at first, and get out. So, if I just unplug the wire, that will create a bigger problem?

If you have an aftermarket alarm, I'm not sure what you could expect by removing it. But if you have the factory alarm system, any tampering will leave you locked out of the car, and the car won't start if you get in. There is a video out there showing a way to deactivate the alarm system for the Accord at the fuse panel inside the driver kick panel.