RepairPal Certified shops can diagnose and repair your 2000 Ford F-250 Super Duty. They provide transparent pricing with a minimum 12-month or 12,000-mile warranty on repairs and services.
Ford has a live misfire detection strategy that is very good at first identifying the cylinder(s) that is(are) misfiring. Has anyone identified the cylinder(s) responsible for the symptom? From there what testing has been done? Is it missing spark, fuel or compression?