Ford F-250 Super Duty engine shuts off while driving, issue unresolved after multiple mechanic visits on Ford F-250 Super Duty

Submitted by Vehicle Owner · Jun 23, 2025
Published by RepairPal

Problem overview

Some Ford F-250 Super Duty owners report experiencing engine shutdowns while driving, which can be frustrating and potentially dangerous. These shutdowns may be caused by contaminated gasoline, particularly if the issue occurs shortly after refueling. Additionally, a faulty camshaft sensor has been known to lead to unexpected engine shutdowns, necessitating replacement for resolution. Electrical issues, including problems with engine cover gaskets, harnesses, glow plugs, and relays, can also contribute to intermittent shutdowns. Furthermore, fuel system problems, such as a failing fuel pump or clogged fuel filter, may require thorough inspection to identify the cause. Some owners have noted that a weak high-pressure oil pump (HPOP) can prevent the engine from restarting after being turned off when hot, indicating the need for careful inspection of the Injector Pressure Regulator wiring. If the engine shutdown problem persists despite multiple mechanic visits, seeking a second opinion from a specialized Ford technician is recommended for comprehensive diagnostics and effective troubleshooting.

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