Infotainment system completely out and re-booting did not help

Hello, check for any blown fuses - in case it's preventing the unit from powering up. Beyond that, removal and inspection to ensure it's getting power is a a start, plus using a diagnostic tool to check for concerns. It could be that there is an internal issue - but it's hard to say. Start with testing. https://repairpal.com/auto-repair-near-me