My key won't start the van or turn somtimes. The steering locked,the shift locke

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The batt.is fine( new) starter fine Starts with the remote. Keys are fine have 3 different ones all have worked fine before.The van is lock happy, you don't dare get out without the key in your hand somtimes it locks & somtimes it don't I don't think this has anything to do with the starting problem Please Advise !!