Spark plug wires

Hello, which engine is your 1500 equipped with? No code will ever show "spark plug wire" as a cause of failure. It will show a misfire code, perhaps a P0304 code showing cylinder 4 misfire, but there are multiple possible causes for a misfiring cylinder. Yes, a failed spark plug or ignition wire could be the source of failure, but also fuel injector or even a concern within the valve train in the cylinder head or the cylinder itself in the engine could be a concern. What testing has been performed? An easy "backyard mechanic" check is to swap ignition wires from cylinder 4 to cylinder 3, and spark plug from cylinder 4 to cylinder 2 -- and seeing if the misfire stays with 4, goes to 3 or goes to 2. Then you can see what component is leading to concerns -- if it's related to plugs and wires. How many miles are on your Chevy Truck?