Ford E-350 Super Duty engine cut out issue resembling spark knocking on Ford E-350 Super Duty

Some Ford E-350 Super Duty owners report experiencing engine cut out issues that resemble spark knocking, which may be linked to several factors. These issues could stem from spark plug problems, particularly in vehicles with a V-10 gas engine or a 5.4 V8 engine. Additionally, ignition coil malfunctions can lead to misfires and subsequent engine cut outs. Owners also note that fuel system issues or a lack of throttle body cleanliness might contribute to these engine performance problems. To address these concerns, some owners recommend inspecting ignition coils and spark plugs for damage, as well as ensuring fuel injectors and the throttle body are clean. Regular maintenance, including the timely replacement of ignition components and ensuring proper ventilation in the engine compartment, is advised to help prevent these engine cut out scenarios.