Q: MY mercedes benz check engine light came on when i was driving it could it be sp on 2002 Mercedes-Benz ML500

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sparkplug need to be change
(1) Answer
If the check engine light came on for a Misfire, then spark plugs "could" be the problem, but its just one of many possibilities.
However, there are many other faults that can trip a Check Engine Light besides misfires, so your best bet would be to have the engine computer scanned for fault codes and go from there.