Misfire, Hesitation, Rough Running from Engine, Notably After Ignition Wire Replacement on Ford E-350 Super Duty

The engine may have a misfire, hesitation, and/or run roughly – notably after a service and/or ignition wire replacement. If after recent ignition wire replacement, the cause can be misrouted ignition wires. The wires from the distributor to the valve cover must be routed correctly to avoid interference and induction crossfire. Verify all clips are used to secure and separate ignition wires.