Ram 1500 engine light on with rough running due to cylinder #3 misfire code P0303 on Ram 1500

Submitted by Vehicle Owner · Jun 23, 2025
Published by RepairPal

Problem overview

Some Ram 1500 owners report experiencing engine issues when the check engine light illuminates, particularly related to a cylinder #3 misfire indicated by trouble code P0303. This misfire can stem from common causes such as a faulty ignition coil or spark plug, vacuum leaks, or a malfunctioning fuel injector. Owners have noted that a misfire in cylinder 3 may result in a loss of power, poor engine performance, decreased fuel efficiency, and potential engine damage if not addressed promptly. Identifying the root cause, whether it be faulty spark plugs, ignition coils, fuel injectors, or compression issues, is essential for effective repairs. It is crucial for owners to address this issue quickly to prevent further engine damage and maintain optimal vehicle performance. Consulting a qualified mechanic for diagnosis and repairs is recommended for those experiencing these symptoms.

2 people reported this problem
1 comment
Schedule Repair

Ram 1500 vehicles with this problem

1 model year affected
Average mileage: 37,000 miles
(37,000 - 37,000)

Search for another problem

RepairPal Car Genius

Ask our experts about your Ram.

RepairPal Car Genius™ is a free resource for vehicle owners seeking advice on maintenance, auto repair, shop inquiries, estimates, and finding a trustworthy repair shop in your area.

 Auto Repair Expert Auto Repair Expert

Call us at 877-913-1554

Available 9am – 6pm ET Monday through Friday

Call Our Experts