ECM needs to be replaced on Toyota Sienna

Problem Description

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2001 Toyota Sienna - 3.0L V6 160,000 mi,
ABS light on, Speedo doesn't work, trans has erratic shifts

2000 Toyota Sienna - 3.0L V6 140,000 mi,
Van just cut out, will not start up again, ECM replaced, problem repeated just after 35 miles. Mechanic on his way to pick up vehicle.