Mercedes-Benz ML350 delayed starting issues with intermittent no response from ignition key on Mercedes-Benz ML350

Submitted by archytype · Jun 23, 2025
Published by RepairPal

Problem overview

Some Mercedes-Benz ML350 owners report experiencing delayed starting issues and intermittent no response from the ignition key. These problems may stem from a communication issue between the electronic key and the ignition module. Additionally, electrical problems related to the gear selector can contribute to these frustrating starting difficulties. Some owners also encounter issues with the key fob, which may sporadically fail to be recognized. In certain cases, checking and replacing blown fuses associated with the electronic ignition system has resolved starting issues. Furthermore, there are instances where the replacement of the Electronic Control Module (ECM) was necessary, although this can be a costly fix. While some DIY tests may be attempted, it is advisable for owners to seek assistance from a qualified technician or a Mercedes-Benz dealership for more complex issues, such as reprogramming the ignition system module. Addressing these potential causes systematically is crucial for resolving the starting problems in the ML350.

9 people reported this problem
6 comments
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Mercedes-Benz ML350 vehicles with this problem

Average mileage: 64,366 miles
(35,200 - 86,000)

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