Mercedes-Benz ML350 delayed starting issues with intermittent no response from ignition key on Mercedes-Benz ML350

Submitted by archytype · Jun 23, 2025
Published by RepairPal

Problem overview

Some Mercedes-Benz ML350 owners report experiencing delayed starting issues, including intermittent no response from the ignition key. These problems may stem from a communication issue between the electronic key and the ignition module. Additionally, some owners find that electrical problems related to the gear selector contribute to these frustrating starting difficulties. In certain cases, checking and replacing blown fuses, such as the 7.5 amp fuse for the Electronic Ignition System (EIS), has resolved starting problems. If diagnosed with a faulty Engine Control Module (ECM), replacing it could potentially fix the intermittent starting issues, albeit at a high cost. Furthermore, reprogramming the EIS module may help address no-start conditions. It is advisable for owners to seek help from a qualified technician or a Mercedes-Benz dealership for complex procedures like reprogramming, as these require technical expertise and specialized tools. Promptly addressing these issues is crucial to ensure the vehicle's proper functioning and to avoid potential breakdowns or safety hazards.

155 people reported this problem
74 comments
Schedule Repair

Search for another problem

RepairPal Car Genius

Ask our experts about your Mercedes-Benz.

RepairPal Car Genius™ is a free resource for vehicle owners seeking advice on maintenance, auto repair, shop inquiries, estimates, and finding a trustworthy repair shop in your area.

 Auto Repair Expert Auto Repair Expert

Call us at 877-913-1554

Available 9am – 6pm ET Monday through Friday

Call Our Experts