Some Mercedes-Benz E550 owners report experiencing a rumbling noise from the rear differential that increases with speed, which may indicate differential trouble such as worn-out bearings or insufficient lubrication. These owners note that persistent whining or humming noises while driving, particularly during turns, are common signs of differential issues. Additionally, clunking or clicking noises during driving, especially when making sharp turns or sudden speed changes, can signal damaged or worn-out differential components. Ignoring these sounds can lead to serious problems within the differential that require immediate attention to prevent further damage and ensure safe operation of the vehicle. It is advisable for owners experiencing these symptoms to have the rear differential inspected by a qualified mechanic to accurately diagnose and address the issue.
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