Mercedes-Benz ML320 runs rough after 10-12 miles, issue not corrected on Mercedes-Benz ML320

Submitted by Vehicle Owner · Jun 23, 2025
Published by RepairPal

Problem overview

Some Mercedes-Benz ML320 owners report experiencing rough running conditions after driving 10-12 miles, which can be attributed to various underlying issues. These owners have noted that problems within the fuel system, such as a clogged fuel filter or a malfunctioning fuel pump, may lead to these performance issues. Additionally, issues with the ignition system, including faulty spark plugs or ignition coils, can also contribute to rough idling after a certain distance. Some owners have found that even after replacing the EGR valve, the vehicle continues to run roughly, suggesting other related components may be at fault. Furthermore, a dirty air filter can impact engine performance and cause rough idling, while deteriorating spark plug wires, especially as the vehicle ages around 80,000 miles, can lead to misfire codes. To resolve these persistent issues, it is advisable for owners to systematically inspect and replace components within the fuel, ignition, and air intake systems, ensuring optimal performance and a smoother driving experience. Regular maintenance and timely replacements of worn-out parts are essential for addressing these concerns.

1 person reported this problem
0 comments
Schedule Repair

Mercedes-Benz ML320 vehicles with this problem

0 model year affected

Search for another problem

RepairPal Car Genius

Ask our experts about your Mercedes-Benz.

RepairPal Car Genius™ is a free resource for vehicle owners seeking advice on maintenance, auto repair, shop inquiries, estimates, and finding a trustworthy repair shop in your area.

 Auto Repair Expert Auto Repair Expert

Call us at 877-913-1554

Available 9am – 6pm ET Monday through Friday

Call Our Experts