Mercedes-Benz E350 loud humming noise at highway speeds due to worn left front wheel bearing on Mercedes-Benz E350

Submitted by Vehicle Owner · Jun 23, 2025
Published by RepairPal

Problem overview

Some Mercedes-Benz E350 owners report experiencing a loud humming noise at highway speeds, particularly from the left front wheel bearing, which is often indicative of a worn wheel bearing. This humming noise typically intensifies as the vehicle accelerates, especially noticeable over 50 mph. Owners may diagnose this issue by lifting the car and spinning the wheel to listen for abnormal sounds. The volume of the noise tends to increase with speed, making it more pronounced during highway driving. Factors such as lack of lubrication, contamination, or general wear and tear can lead to wheel bearing failure. It is crucial for owners to address this issue promptly, as a faulty wheel bearing can pose safety risks and negatively impact driving comfort. Consulting a qualified mechanic for inspection and replacement is advisable to ensure safety and optimal vehicle performance.

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Mercedes-Benz E350 vehicles with this problem

1 model year affected
Average mileage: 61,000 miles
(61,000 - 61,000)

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