The electrical connector at the automatic transmission may leak fluid into the wiring harness. If not repaired, the oil will migrate through the wiring harness and damage the transmission control module. A new harness and control module may be necessary to correct this problem.
Car problem reports
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Most reported 2006 Mercedes-Benz E500 4MATIC problems
The ESP and BAS warning lights may illuminate due to a failed brake light switch. Replacement of the failed switch should correct this concern.
Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.
The release tab for the center console can fall off unexpectedly.
An engine oil leak may develop from the oil level sensor. Replacement of the leaking sensor will commonly correct this concern.
Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.
An engine Oil leak may develop from the PCV vent housing on the valve cover and/or the inspection plate on the front of the engine.
The relay which turns the airmatic suspension pump on may fail causing the pump to run continuously. This can result in failure of the pump motor or a dead battery as the pump motor will continue to run after the car is turned off. Also, Worn airmatic pump mount bushings can causes noises in the front axle while driving on bumpy roads or a buzzing noise while the pump is running.
Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.
Many software updates are available for the different computer systems, but if the vehicle is out of warranty, it may cost money to receive the updates (unless it is a recall). Some updates may be dealer-only, but a well-equipped independent shop can usually provide updates as well.
A failed digital heater control valve can cause a lack of heat output from the climate control system.