Due to wear, high usage vehicles can experience ignition lock and tumbler failures. The ignition lock cylinder will generally require replacement to correct this concern.
Car problem reports
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Most reported 2001 Mercedes-Benz E430 problems
The brakes may begin to squeak at about the 50 percent wear point. This is due to the size and material used for the brake pads and rotors. The brake rotor surfaces become uneven, causing a lip to form at the outer edge. This will generally require replacement of the rotors when the pads are worn (pad life varies depending on driving style and terrain).
An engine oil leak may develop from the oil level sensor. Replacement of the leaking sensor will commonly correct this concern.
An engine Oil leak may develop from the PCV vent housing on the valve cover and/or the inspection plate on the front of the engine.
A vibration felt through the center floor of the vehicle can be caused by cracked and/or shredded driveshaft flex discs, resulting in excessive driveshaft movement. If not repaired, damage to the driveshaft center support bearing, transmission, or differential can occur.
The rubber bond in the harmonic balancer can decay, which causes the balancer to move and work its way toward the timing cover. If the balancer comes into contact with the timing cover while the engine is running, it will fracture and damage the cover and potentially other surrounding parts. The harmonic balancer should be inspected at every service.