The engine may develop a stalling and/or no start condition due to a failed crankshaft position sensor.
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Most reported 2005 Mercedes-Benz E320 4MATIC problems
An engine Oil leak may develop from the PCV vent housing on the valve cover and/or the inspection plate on the front of the engine.
An engine oil leak may develop from the oil level sensor. Replacement of the leaking sensor will commonly correct this concern.
The rubber bond in the harmonic balancer can decay, which causes the balancer to move and work its way toward the timing cover. If the balancer comes into contact with the timing cover while the engine is running, it will fracture and damage the cover and potentially other surrounding parts. The harmonic balancer should be inspected at every service.
High mileage or older vehicles commonly develop leaks from the differential seals and/or cover. Our technicians recommend a complete reseal of the differential unit whenever these leaks are repaired.
Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.
The cup holder in the center console may break.
Many software updates are available for the different computer systems, but if the vehicle is out of warranty, it may cost money to receive the updates (unless it is a recall). Some updates may be dealer-only, but a well-equipped independent shop can usually provide updates as well.
Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.
This vehicle has sensotronic brake control (SBC). If the SBC light on the dash illuminates, have the brakes checked. If the SBC is not working, limited brake pressure is delivered to the front brakes, increasing the distance it takes to stop. The SBC hydraulic unit has a specific service life programmed into the control module; follow the manufacturer's recommended service procedure for proper maintenance of the SBC.
A failed digital heater control valve can cause a lack of heat output from the climate control system.
Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.