Due to wear, high usage vehicles can experience ignition lock and tumbler failures. The ignition lock cylinder will generally require replacement to correct this concern.
Problems for specific Mercedes-Benz E320 years:
Car problem reports
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Most reported 1994 Mercedes-Benz E320 problems
High mileage vehicles may develop a leak from one or more of the transmission oil seals.
The bushings for the shifter lever wear out to the point where they break and fall out. This causes excessive movement (loose feel) in the shifter lever and a clanging-type noise when changing gears.
The brakes may begin to squeak at about the 50 percent wear point. This is due to the size and material used for the brake pads and rotors. The brake rotor surfaces become uneven, causing a lip to form at the outer edge. This will generally require replacement of the rotors when the pads are worn (pad life varies depending on driving style and terrain).
The engine wiring can degrade because the insulating material falls off leaving the bare wire exposed. This can cause many problems depending on which wires are exposed and what they touch.
Motor mounts commonly fail, causing engine vibrations to be transferred to the body. Failed motor mounts should be replaced in order to prevent damage to the transmission mount.
The emissions air injection pump can seize, causing a loud squealing noise followed by smoke from the drive belt. If the engine is not turned off, the belt will break, turning on the alternator/battery warning light.
A coolant leak may develop form the Radiator due to degradation of its plastic components. Replacement of the failed radiator will be necessary.
A coolant leak may develop from the water pump. When replacing the water pump, the drive belt tensioner should be inspected and most likely replaced as well.
Vehicles with automatic level control that ride harshly in the rear (no give in the suspension) may have one or both dampening actuators which have failed. It is commonly recommended the actuators be replaced in pairs.
The sunroof may not work correctly due to failed components as a result of age and wear. Repairing a sunroof can be labor intensive and very costly.