The cup holder in the center console may break.
Car problem reports
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Most reported 2005 Mercedes-Benz E500 problems
Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.
The release tab for the center console can fall off unexpectedly.
A failed digital heater control valve can cause a lack of heat output from the climate control system.
The crankshaft position sensor may fail. Symptoms of this are: The engine will crank—but not start—especially when the engine is warm. The car may start again if it is left to cool off, but it may run roughly or have poor performance. Communicating these specific symptoms to your technician can save diagnostic time.
The electrical connector at the automatic transmission may leak fluid into the wiring harness. If not repaired, the oil will migrate through the wiring harness and damage the transmission control module. At that point, a new harness and control module may be necessary to correct this problem.
This vehicle has sensotronic brake control (SBC). If the SBC light on the dash illuminates, have the brakes checked. If the SBC is not working, limited brake pressure is delivered to the front brakes, increasing the distance it takes to stop. The SBC hydraulic unit has a specific service life programmed into the control module; follow the manufacturer's recommended service procedure for proper maintenance of the SBC.
The early versions of the central gateway module (which allows different systems to communicate with each other) have software problems.
The relay which turns the airmatic suspension pump on may fail causing the pump to run continuously. This can result in failure of the pump motor or a dead battery as the pump motor will continue to run after the car is turned off. Also, Worn airmatic pump mount bushings can causes noises in the front axle while driving on bumpy roads or a buzzing noise while the pump is running.
Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
A vibration felt through the center floor of the vehicle can be caused by driveshaft flex discs, which crack and shred, causing excessive driveshaft movement. Not repairing these can cause damage to the driveshaft center support bearing, or, in the worst case scenario, damage to the transmission or differential.
Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.