Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
Car problem reports
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Most reported 2008 Mercedes-Benz CLS63 AMG problems
Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.
The ESP and BAS warning lights may illuminate due to a failed brake light switch. Replacement of the failed switch should correct this concern.
Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.
The relay which turns the airmatic suspension pump on may fail causing the pump to run continuously. This can result in failure of the pump motor or a dead battery as the pump motor will continue to run after the car is turned off. Also, Worn airmatic pump mount bushings can causes noises in the front axle while driving on bumpy roads or a buzzing noise while the pump is running.
A vibration felt through the center floor of the vehicle can be caused by driveshaft flex discs, which crack and shred, causing excessive driveshaft movement. Not repairing these can cause damage to the driveshaft center support bearing, or, in the worst case scenario, damage to the transmission or differential.
Many software updates are available for the different computer systems, but if the vehicle is out of warranty, it may cost money to receive the updates (unless it is a recall). Some updates may be dealer-only, but a well-equipped independent shop can usually provide updates as well.
Due to the size and material used on the brakes of these vehicles, the brakes may start to squeak around the 50 percent wear point. The brake rotor surfaces become uneven, causing a lip to form at the outer edge of the rotor. Because of this, the rotors are usually replaced when the pads are worn (pad life varies depending on driving style and terrain).
The early versions of the central gateway module (which allows different systems to communicate with each other) have software problems.