The cooler for the EGR valve can leak coolant internally, which causes white smoke to come from the tail pipe. Hot exhaust gases are cooled by the EGR cooler before being circled back into the engine.
2011 Ford F-250 Super Duty Problem Reports
Most Reported 2011 Ford F-250 Super Duty Problem Reports
A coolant leak from the radiator can be caused by a defective thermostat bypass. This can cause pressure spikes in the cooling system, which leads to radiator failure. The thermostat assembly and radiator should be replaced.
The high pressure diesel fuel injection pump may fail, resulting in a "no start" condition.