A coolant leak from the radiator can be caused by a defective thermostat bypass. This can cause pressure spikes in the cooling system, which leads to radiator failure. The thermostat assembly and radiator should be replaced.
Problems for specific Ford F-250 Super Duty years:
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Most reported 2010 Ford F-250 Super Duty problems
Software enhancements are available to remedy inconsistency and confusion about the Diesel Particulate Filter (DPF) cleaning cycle - “Regeneration” mode. The Powertrain Control Module (PCM) will need to be reprogrammed to add several enhancements, including a more reasonable driving experience during the cleaning cycle and instrument cluster notifications of the cleaning status.
If the engine cranks but will not start, this may be caused by damaged wiring to the high pressure fuel pump. Wiring to the pump can be chafed, which causes the pump to stop working. The chafed wires will need to be accessed and repaired.
If the driveline angle is out of adjustment, it can cause shuddering from the vehicle when accelerating from a stop. The driveline angle should be adjusted to reduce vibration in most driving conditions.