Overheating and/or lack of proper venting can cause the rear axle seals to leak. Excessive fluid loss can result in major damage to the rear differential assembly and/or axle bearings.
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Most reported 2005 Nissan Titan problems
after about 200 miles of constant driving vehicle would jerk very badly as if transmission were slipping. Just found a TSB for pump failure under full acceleration. replaced no problems since- pending