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Q:

service engine light on 2006 Mercedes-Benz E350

Rookie cbe0621eac06868b3efe0d8d1d3611e23c60d3114864ea2ec19a68cfbd3eebab
what does it mean when service engine light is on?
(1) Answer
This is likely a check engine light: http://repairpal.com/check-engine-light

However, your car has a very advanced maintenance minder that tells you when you are due for service, so you may just be due for scheduled maintenance. Either way, it's time to visit a shop for service or repair.