The engine may develop a stalling and/or no start condition due to a failed crankshaft position sensor.
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Repairpal verified 2008 Mercedes-Benz E550 4MATIC problems
The camshaft adjuster solenoid (which is related to the variable valve timing system) may fail or timing chain/balance shaft components may wear, resulting in illumination of the Check Engine Light and various drivability issues. Mercedes-Benz has released a service bulletin outlining specific repair instructions depending on fault codes stored.
The release tab for the center console can fall off unexpectedly.
Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.
A failed digital heater control valve can cause a lack of heat output from the climate control system.
Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.
The early versions of the central gateway module (which allows different systems to communicate with each other) have software problems.
Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.
The relay which turns the airmatic suspension pump on may fail causing the pump to run continuously. This can result in failure of the pump motor or a dead battery as the pump motor will continue to run after the car is turned off. Also, Worn airmatic pump mount bushings can causes noises in the front axle while driving on bumpy roads or a buzzing noise while the pump is running.
Vehicles equipped with a 7-speed automatic transmission may develop a rough shifting condition, most commonly going up from first to second gear and going down from third to second or second to first gear. Our technicians tell us this is due to an internal component failure. Mercedes has released updated parts; the transmission will need to be removed and disassembled to complete the necessary repairs.
Due to the size and material used on the brakes of these vehicles, the brakes may start to squeak around the 50 percent wear point. The brake rotor surfaces become uneven, causing a lip to form at the outer edge of the rotor. Because of this, the rotors are usually replaced when the pads are worn (pad life varies depending on driving style and terrain).
High mileage or older vehicles commonly develop leaks from the differential seals and/or cover. Our technicians recommend a complete reseal of the differential unit whenever these leaks are repaired.
The cup holder in the center console may break.