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Q: I have two codes 0446 and 0420 on 1999 Lexus ES300

I have both codes and what may be wrong, but there is a list of like 50 things it could be between the two codes... The problem is that the car starts and all but when I put it in gear, R,D,2,1 it will not engage... The other day I was driving and it just basically felt like the car was in neutral while in drive, push the gas and RPMs go up but the car doesn't gain speed or basically respond at all...Also I have check engine light on as well as the trac light being on... I really have no idea as to what direction to go in i have 140K+ miles on it. I had hoped there would be an easy fix and cheap solution for this. Any ideas or suggestions as to what steps to go in?
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