Q: Humming Noise from Bottom on 2007 Lexus ES350

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My car recently producing some kind of noise like deep base humming sound while driving and it seems coming from the bottom of the car. I wonder if it is possible from the transmission. The sound is gone when car not moving. Any suggestion? Thanks
(1) Answer
Could be alot of things. Does it go away when you turn left or right. If it goes away when you turn in one direction and comes back in the other it could be a wheel bearing. If its there constantly when driving it could be drivetrain related. How many miles are on the vehicle? There is one bulletin pertaining to a droning noise which has to do with your active engine mounts. This requires replacment of the mounts.