Q: Do you have to use a special freon and guages/hose due to it being a hybrid on 2007 Nissan Altima Hybrid

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Was told u could mess up the electrical system if the r134a was used
(2) Answers
IF the A/C compressor is belt driven AND electrically run (when gasoline engine is stopped) then YES you DO need a Different kind of OIL for the system , although the refrigerant is still R-134. NO BULL bet-check with dealer/Nissan tech ,before making the wrong (and possibly very expensive) mistake.
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