Q: after the start and run, temp are normal, but in 1&1/2mile,the temp getting high on 2000 Mercedes-Benz E320

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it reach 110 in very normal condition (that's in temp reading)
(1) Answer
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It could be a stuck thermostat or a problem with one of the electric cool fans. You need to get it a shop and have it checked out. Make sure the coolant level is full!