will not start wants to start but acts like not getting fire on 2006 Ford Ranger

it backfired threw the intake upone first start up with new short block ran for 20 min back fireing threw the intake and shut off no will not start. its a 2006 for ranger with a 3.0 v6 brand new short block

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2 answers
I agree with#1 scan test it to see if there any codes
Re-check valve timing and ignition firing order?..............Short block not from Advance Auto is it?