what to due as part of a tune up on 2003 Lexus LS430

I keep up with oil and tires, did fuel injector cleaner 4 months ago, but haven't done a tune up in a while, what should I consider in the tune up, spark plugs, another fuel injection clean? raidiator flush? what else? trying to avoid unnecassary expense.

Asked by for the 2003 Lexus LS430