If the engine is running rough make sure the valve clearances are checked cold on that engine (very frequently over looked and causes a problem on that engine). Lots of the fuel injector cleaners are good and it is OK to increase the concentration of the cleaner but nothing beats flushing the injectors under pressure.
An engine motorvac or carbon depletion are the best choices. This service must be done at a shop with the right equipment to perform the service. If you are looking for something to put into the gas tank and get results from, BG44K is the best choice.