What causes engine to crank/but not start? Acts like it is not getting fuel, on 2007 Isuzu i290 Pickup

It cranks without firing, get frustrated and wait a few minutes and it starts. What is the issue?

Get Your Car Fixed at a RepairPal Certified Shop.
We certify shops based on expertise, quality work, and verified customer reviews
2 answers
Try holding throttle down about half way and see if it starts better!
No answer for me, just wondering if you've found any????