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Q:

what causes cylinders 5 thru 8 to misfire check eng lite flashes on 1998 Mercedes-Benz S500

Rookie cbe0621eac06868b3efe0d8d1d3611e23c60d3114864ea2ec19a68cfbd3eebab
on start up car has no power ran fine before problem started after been parked for couple of weeks
(2) Answers
review when last tuned. it may be due.
rec. fuel system clean. ethanol treatment to 1 tank premium fuel. ethanol blend in fuel causes build up in fuel system, combustion chambers, exhaust system and causes increased wear to spark plugs.
rec. oil stabilizer treatment with next oil change. recondition cylinders and seals(improve compression).
Hi,

I could be multiple things like a vacuum leak, mass air flow meter the left bank's O2 sensors...

Scan the codes.

Also inspect the engine harness for shorts and deterioration.

Good luck!