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Try a full fuel system cleaner with injector cleaner first and see if this helps. Best way is to pull injectors and clean by hand but, lets not jump the gun yet.
Get battery and alternator tested. Battery first at a parts store they will charge and test for free. If it holds charge I would start looking at the alternator.
Hope this helps you: http://www.fixya.com/cars/t1657176-toyota_t100_obdii_code_p0450_pressure
Not sure what you are asking but, If I am guessing right, no. Nut at center is on driveshaft (half-shaft) does not need to be removed. Loosen slider pins on brake calipers and remove. Then loosen bolts and remove caliper mounting bracket. Compress caliper cylinder to maximize space for rotor. Use a wire or rope to suspend caliper in air, so not to stress flexible brake line. Rotor may have a factory set screw in it that needs removed. Otherwise, just tap on rotor till it breaks free and install new one and reverse process.
Most likely, is that your transmission range sensor has gone bad. It is reading a gear other than what you are in and thus, the two are no longer in sync. Need to put a new transmission range sensor in. http://www.2carpros.com/forum/automotive_pictures/99387_Graphic9_30.jpg
Check your trans. fluid level. Changing the fluid and putting in fresh could help with this problem.
Best to check starter motor and if that is okay have ignition switch checked.
I would suggest a bosch premium oil filter and go with valvoline full synthetic motor oil. Stick to your recommended oil weight for your vechicle.
Please post the engine code that would make it easier. Otherwise, could be the spark plugs or coils. Need code please.
Need to know what those codes were. I'm betting they were o2 sensor codes, but please post the check engine codes.