On higher mileage vehicles, an engine misfire may develop and/or the Check Engine Light may illuminate due to a failed ignition coil. It is not uncommon to replace all the coils when the first one fails in order to prevent return trips to the repair shop.
Problems for specific Toyota Avalon years:
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Newest reported 2005 Toyota Avalon problems
A loss of power on the freeway may due to an internally leaking fuel pulsation dampener. This commonly occurs on higher mileage vehicles.
Toyota issued a recall on one of the connections in the steering shaft that was not welded properly, which could cause steering problems. This can be repaired free of charge at a Toyota dealership. The recall applies to only certain 2005 models only.