Reliability of this model E350 on 2010 Mercedes-Benz E350 4MATIC

Might buy a CPO w/22k miles, though read dozens of posts, of really bad issues, like going through 5 sets of tires in 73k miles due to engine weight on front end, cracked driveshaft flex discs, air suspension leaking, brakes AND pads need fequent replacement, air susp, relay causing dead battery etc... in general, should I steer way clear of this model / MB ? Thanks, leaning that way-heavily. Regards

Asked by for the 2010 Mercedes-Benz E350 4MATIC
mbz are nit really a good dependable car at all. they are money pits after 36k miles. lexus, toyota or honda